Category Archives: Research

Alzheimer’s – some optimism #ENDALZ

Failed clinical trials and the continued lack of money for research leaves me with a feeling of pessimism. Bill and Melinda Gates getting involved is big to me, as they announced they are going to help scientists examine other theories. The longitudinal study in Columbia is exciting because they feel certain that everyone in the study will get alzheimer’s. The NIH is setting aside some money for new scientists, with fresh ideas. Thoughts of those things brings a feeling of optimism.

Hearing success stories from caregivers, accounts of them adapting, reading about laws being passed that may help them, and reading about the growth of support groups, memory cafes and more community involvement brings optimism.

Reading that our nation, as a whole, is eating healthier and exercising more is great news. That’s talk about prevention right there, good talk.

A lot of progress has been made in many areas. Necessity, sometimes, can be the mother of invention.

Research – different paths sounds interesting

A few months ago I took a trip to the Burrell School of Osteopathic Medicine in Las Cruces New Mexico. What I saw made me realize we are trying alternative ways to prevent, treat and cure disease.

Recently Bill Gates told Maria Shriver that he was using his resources to work with folks concerning Alzheimer’s research that are walking down different paths , than the norm.


I was introduced to scientists at UAMS, OMRF, CU Medical School and the Columbus Memory Center.

The University of Colorado Anschutz Medical Campus in Aurora.

The Oklahoma Medical Research Foundation in Oklahoma City

Near the University of Arkansas Medical School in Little Rock

The Columbus Memory Center in Columbus Georgia

The University of Colorado Anschutz Medical Campus in Aurora

The University of Arkansas Medical School in Little Rock

The University of Arkansas Medical School in Little Rock

The University of Arkansas Medical School in Little Rock

the buck stops there #ENDALZ

According to the Alzheimer’s Association, America has 1,309 new diagnosis every day, yeah, you read that right, every day.

It’s estimated that we have more than five million people, in America, with dementia. It’s also estimated that by 2050, we will have over 15 million.

Who’s driving this train. The director of the National Institute of Health is. From my point of view, this man has a huge responsibility. I don’t really know much about him. I say this very respectfully, I hope he is up to the task.

Francis S. Collins M.D. , Ph.D is the Director. He has occupied that office and title since August 17, 2009.

search for a treatment, or a cure for alzheimer’s – a sense of urgency

“We are not, at the moment, limited by ideas. We are not limited by scientific opportunities. We are not limited by talent. We are, unfortunately, limited by resources to be able to move this Enterprise forward at the pace that it could take.” Frances S. Collins M.D. , Ph.D.

Mr. Collins has his finger on the pulse of this situation. Mr. Collins, a Geneticist, is the Director of the National Institute of Health.

Personally, trying to remain positive, left aside, and focusing on how I view the reality of our current situation, this is my opinion.

Treatment or a cure for alzheimer’s disease may have as many as ten viable theories, but we may have research dollars to fully examine only two or three.

We need more dollars or a lot of luck, or maybe some of both.

The Alzheimer’s Association estimated that alzheimer’s disease cost America $259 billion dollars in 2017, and less than $1.3 billion was marked for research.

Another personal observation: The Sense of Urgency, in the public, in the press and coming from our legislative bodies doesn’t feel strong. The Sense of Urgency amongst Advocates is to be admired.

this amazes me #ENDALZ

to see the pictures comparing a brain free from alzheimer’s to one in the latter years of the disease.

I see these and realize some of ladies in the Nun Study had full blown alzheimer’s, the plaques and tangles were everywhere, but they still had tremendous cognitive abilities. Fascinating, absolutely fascinating!

diagnosing alzheimer’s may soon become cheaper

Australia announced they’ve identified certain fragments of proteins, that, when found in the blood, mean amyloid proteins are building up in the brain.

The paragraph above comes from the article, the link below, will take you to.

My thanks to the Mayo Clinic for tweeting this.

Life expectancy?????

Four elderly folks – age at death was 86, 82, 78 and 74. The average age at death was 80 years old.

Now four children – age at death was 5, 4, 3 and 2. The average age at death was 3.5 years old.

The average at of death of all eight was 41.75 years old.

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Now let’s improve the age of the children. The improved age of the children at death was 12, 11, 10 and 9 years old. The average age at death was 10.5 years old.

The new and improved average age of death of all eight was 45.25 years old.

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The average at death of all participants improved from 41.75 years to 45.25 years.

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Are the adults in my example living longer? No, and that’s obvious, but when we read some studies we have to make sure what the writer meant. In my make believe story, things improved for the little guys, but not for the elderly ones.

I just asked Google for the life expectancy for America for someone born in 1900, and it said 47 years of age. The average age at death of my grandparents was 78 years old and they were all born around 1900. Did Google take into account everybody? Are my circumstances rare? Remember, back then, the approximate infant mortality rate was 100 deaths per every one thousand births. Now the approximate infant mortality rate is around 5 deaths per every one thousand births.

This tells me the folks trying to figure stuff out for us, have a lot to consider.

from the NIA (Laurie Ryan Ph.D)

You may have already heard that the NIA has awarded a new cooperative agreement establishing the Alzheimer’s Clinical Trial Consortium (ACTC). We expect the ACTC to accelerate and expand studies for therapies in Alzheimer’s disease and related dementias.

That paragraph was taken from the article the link below will take you to.

Maria Shriver and Bill Gates @TODAYshow – #ENDALZ

@TODAYshow posted this on Facebook this morning.